How to Fix “No active antivirus provider” on Windows 10 Posted on October 7, 2022October 7, 2022 by Summa Lai The issue was due to ‘DisableAntiSpyware’ registry key under HKLM:\SOFTWARE\Policies\Microsoft\Windows Defender which was set to 1. This has to be changed to 0. And this will enable Microsoft Defender as the active antivirus.